What are the bounds on the Individual Treatment Effect (ITE) of smoking π¬ vs. not smoking π on COPD π«, given only one observed background variable β whether the parents smoke?
Under the Monotonicity Assumption, we assume that having smoking parents π€ can only increase a childβs risk of developing COPD π« through passive exposure.

By God-Given knowledge we have access to the true counterfactual outcomes for each individual for smoking π¬ and for not smoking π
This gives us 4 Compliers: people who get COPD only if they smoke, and avoid it otherwise. It also goes by the name PNS: Probability of Necessity and Sufficiensy:
\(\text{PNS} = \frac{4}{16} = 0.25\)
By God-Given knowledge we have access to the true counterfactual outcomes for each individual for smoking π¬ and for not smoking π
This gives us 4 Compliers: people who get COPD only if they smoke, and avoid it otherwise. It also goes by the name PNS: Probability of Necessity and Sufficiensy:
\(\text{PNS} = \frac{4}{16} = 0.25\)
\[ 0 \le \text{PNS} \le \]
\[ 0 \le \text{PNS} \le \frac{4}{16} + \]
In order to bound PNS we need to count the possible proportion of Compliers:
The total number of observed non-events without treatment, they might be Compliers or Never-Takers.
\[ 0 \le \text{PNS} \le \frac{4}{16} + \frac{7}{16} \]
In order to bound PNS we need to count the possible proportion of Compliers:
The total number of observed non-events without treatment, they might be Compliers or Never-Takers.
The total number of observed events with treatment, they might be Compliers or Always-Takers.
\[ 0 \le \text{PNS} \le \frac{11}{16} \] Now we know the bounds of the PNS.
It resonates with our true βGod-Givenβ PNS:
\[ 0 \le \text{PNS} = \frac{4}{16} \le \frac{11}{16} \]
\[ 0 \le \text{PNS | Smoking-Parents} \le \text{?}\] \[ 0 \le \text{PNS | Non-Smoking-Parents} \le \text{?}\]
In order to bound PNS we need to count the possible proportion of Compliers within each Sub-population.
\[\small{0 \le \text{PNS | Non-Smoking-Parents} \le \frac{4}{6}}\]
\[\small{0 \le \text{PNS | Smoking-Parents} \le \frac{7}{10}}\]
\[\small{0 \le \text{PNS | Non-Smoking-Parents = } \frac{2}{6} \le \frac{4}{6}}\]
\[\small{0 \le \text{PNS | Smoking-Parents = } \frac{2}{10} \le \frac{7}{10}}\]